FDA NAMs-Aligned
We are redefining human-centric drug testing through the convergence of 3D bioprinting, microfluidics, and AI. As an Organ-on-Chip Engineer, you will design, prototype, and optimize microphysiological systems that replicate human organ function on miniaturized chips—bridging biology, fluid dynamics, and engineering to accelerate ethical and predictive drug development.
Key Responsibilities
In this role, you will engineer microfluidic environments that mimic human physiology at the organ level, collaborating with biologists, AI scientists, and materials experts to create next-generation Organ-on-Chip platforms aligned with FDA’s New Approach Methodologies (NAMs).
- Design and fabricate microfluidic devices using soft lithography, laser ablation, or hybrid manufacturing techniques.
- Develop and validate fluidic networks for perfusion, shear stress control, and nutrient exchange in 3D cell cultures.
- Integrate sensors (optical, electrochemical, or impedance-based) for real-time monitoring of tissue viability and functionality.
- Collaborate with bioengineers to co-culture multiple cell types, creating interconnected “multi-organ” systems for drug metabolism and toxicity studies.
- Work with AI and data teams to automate data acquisition and build predictive models from chip-based experiments.
- Optimize device biocompatibility, sealing, and scalability for long-term operation and reproducible outcomes.
- Maintain experimental records, write technical documentation, and contribute to publications, patents, and regulatory validation studies.
Preferred Qualifications
We are seeking engineers who combine precision fabrication skills with a strong biological intuition.
- PhD or MSc in Microfluidics, Bioengineering, Mechanical Engineering, Biomedical Engineering, or related fields.
- Hands-on experience in soft lithography, PDMS molding, or microfabrication techniques.
- Strong understanding of fluid dynamics, flow control, and microchannel design.
- Familiarity with COMSOL, ANSYS Fluent, or other CFD modeling tools for simulating microscale flow environments.
- Experience with cell culture in microfluidic systems or organ-on-chip platforms.
- Knowledge of materials chemistry, surface functionalization, and bonding techniques for biochip assembly.
- Experience integrating sensors, actuators, or imaging systems for live monitoring is highly desirable.
What We Value
Our foundation is built on the convergence of curiosity, ethics, and excellence. We believe that the future of healthcare innovation depends not just on the technologies we create, but on the values that guide how we create them.
01
Integrity
Every experiment is grounded in rigor, reproducibility, and transparency. We hold ourselves to the highest ethical standards in pursuit of human-relevant science.
02
Innovation
We thrive on asking “why not?” and explore the uncharted spaces where biology meets computation — transforming bold ideas into functional tissue systems.
03
Interdisciplinarity
We unite biology, engineering, and artificial intelligence—transforming cross-disciplinary insight into tangible breakthroughs.
04
Impact
Every printed tissue, every line of code, every experiment moves us closer to a world where drugs are tested safely, efficiently, and humanely — for the benefit of all.
Why Join Z24 Bio
Joining Z24 Bio means becoming part of a deep-tech movement that is transforming how the world discovers, tests, and delivers medicine. We’re not just building tissue models—we’re building the future of human-relevant science.
Every project you lead at Z24 Bio carries real-world impact—from bioprinted tissues that replace animal models to AI that predicts patient safety. Here, innovation isn’t confined to the lab—it drives ethical progress for humanity.
Global Collaboration
Work alongside scientists, engineers, and visionaries from top research institutions and technology hubs across the world.
